BCMB 311 Study Guide - Midterm Guide: Alpha Helix, Amine, Glutamine
16 Dec 2016
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Document Summary
Small organic molecule containing both an amino group and a carboxyl group. S erves as the buildin g block of protei ns. The linking of two amino acids via peptide bond is accompanied by loss of water. Linkage is between the alpha-carboxyl group of one amino acid with the alpha-amino group of another amino acid. A series of amino acids joined by peptide bonds form a polypeptide chain. Positively charged n-terminal end and negatively charged c- terminal end. The variable side chains impact biological properties to polypeptides. Each protein has a unique, precisely defined amino acid sequence specified by its gene nucleotide sequence. Folding pattern, common in many proteins, in which a single polypeptide chain twists around itself to form a rigid cylinder stabilized by hydrogen bonds between every fourth amino acid. Stabilized by hydrogen bonds between the nh and co group of the main chain. The c=o from residue n is hydrogen bonded to the n-h from residue n+4.
