BISC 121Lg Study Guide - Comprehensive Midterm Guide: Lethal Allele, Allele Frequency, Mendelian Inheritance
Document Summary
Mendel favored special creation in opposition to darwin"s theory. Mendel was known for his work with peas: pp x ww. Mendelian inheritance uses laws of probability: alleles segregate independently of other alleles. Inheritance is usually far more complex than in mendel"s peas because many traits are influenced by multiple genes. Thomas hunt morgan"s fruit flies provided the first strong evidence that genes are on chromosomes: he mated male flies with white eyes with female flies with red eyes (wild type) F2 generation had a 3 to 1 ratio of red eyes to white eyes but only the males had white eyes. This led him to believe that the trait for eye color must be sex linked. Examples of sex linked conditions: hemophilia, duchenne muscular dystrophy, color blindness. Each chromosome has hundreds of thousands of genes (except the y chromosome) Recombination frequencies and linkage maps can help determine how likely it is that two genes are linked.
