BIOL 215 Study Guide - Midterm Guide: Blood Proteins, Paracrine Signalling, Osmoreceptor

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Glomerular filtration: as blood, brought in from the afferent arteriole flows through the glomerulus, about 20% of the plasma filters into the bowman"s capsule. What is not filtered leaves via the efferent arteriole. The filtrate contains almost all the same concentrations as in plasma, except cells. The filtrate"s composition is altered by movements of substances from the tubules to the peritubular capillaries (where secretion and reabsorption can occur). Amount excreted (c) = amount filtered (gfr) + amount secreted -amount reabsorbed. Filtrate then goes from the bowman"s capsule down the proximal tubule, through the loop of. Henle, to the distal tubules, to the collecting duct which is connected to the ureter. Glomerular filtration rate: the volume of fluid filtered into bowman"s capsule per unit time. 3 factors: permeability of bowman"s capsule, filtration surface area and filtration pressure (controlled by constriction/dilation of arteriole) How to find out the amount of a substance (s) filtered by bowman"s capsule (filtered load):

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