MCDB 310 Study Guide - Final Guide: Phos, Malonyl-Coa, Squalene
Document Summary
Chapter 19: oxidative phosphorylation (also etc same thing) Importance: promote e- flow through membrane bound carriers, use electron flow to transport protons against their gradient, flow protons across a membrane with its gradient to make atp, know name of complex and which have what prosthetic group. Iron sulfur center in complex 1,2, and 3. Has alpha and beta subunits in it: beta bind atp, adp and pi directly, rotational catalysis model. Chapter 20: photophosphorylation: photosynthesis - 2 phases. Chapter 21: lipid synthesis anabolic: malonyl-coa synthesis, rate limiting step = acetyl coa carboxylase, use biotin prosthetic group, covalently attached to lys. Fa synthesis strategy: adding acetyl coa and malonyl coa. That"s where get 4 carbon backbone: require fa synthase. First step: condensation: activate malonyl coa, nadph coming in to reduce. Lose hydroxyl and proton and add double bond. Fa elongation system: palmitate add 2c at a time.