MCDB 310 Study Guide - Final Guide: Amine, Acetoacetic Acid, Fumaric Acid
23 Apr 2018
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Fat digestion: when eat, broken down by lipases in stomach - acidic environment. Ldl, hdl and vldl - difference = concentration of protein to lipid. Ldl causes plaque formation in arteries, causes heart disease and stroke: glycerol, enters in to cell, activation step first - phosphate added by glycerol kinase. Lock glycerol into cell: glycerol 3-p dh, get more energy out of it, dihydroxyacetone phosphate goes to d-glyc , know pathway => 3 steps, oxidation of fa, stage 1-3, happens in mitochondria. This happens in cytosol: acyl carnitine transporter - goes from cytosol into mitochondria, rate limiting step of acyl chain oxidation. Function is to move fa into mitochondria: malonyl coa is inhibitor. Audio recording started: 7:22 pm sunday, april 22, 2018: beta oxidation (for saturated, step 1: reduction. Make fadh2: step 2: hydration step. Made a double bound and now we get rid of it: step 3: reduction. Make nadh: step 4: acetyl transferase reaction.
