BICD 100 Study Guide - Midterm Guide: Dna-Binding Domain, Epigenetics, Repressor

• School: UCSD
• Department: Biol/Genetics,Cellular & Develop
• Course: BICD 100
• Professor: Keefe Reuther

Document Summary

Gene regulation: not all genes are expressed at all times in all situations, prokaryotic gene regulation. Transcriptional control: whether or not gene is transcribed. Post-translational: change protein activity by chemical modification. Bacteria often respond to environmental change by regulating transcription. Regulate production of enzymes by feedback inhibition/gene regulation. Negative feedback loop example: body temperature/blood sugar regulated. Ex: precu(cid:396)so(cid:396) (cid:271)uilds up t(cid:396)yptopha(cid:374) if you do(cid:374)"t ha(cid:448)e e(cid:374)ough. If you get e(cid:374)ough f(cid:396)o(cid:373) your diet, concentration of tryptophan increases, which signals inhibition of the action of enzymes or inhibition of gene expression. Regulation of gene expression: regulation of enzyme production. Controlling transcription/translation early on; causes a global effect. Operon: entire stretch of dna that includes operator, promoter, and genes they control. U(cid:374)de(cid:396) (cid:272)oo(cid:396)di(cid:374)ated (cid:272)o(cid:374)t(cid:396)ol (cid:271)y a si(cid:374)gle (cid:862)o(cid:374)-off s(cid:449)it(cid:272)h(cid:863) Can be switched off by a protein repressor. Metabolic pathways: catabolic pathways: breaking things down, anabolic pathways: building things up.