NURS 3220 Study Guide - Midterm Guide: Glucocorticoid, Morphine, Respiratory Alkalosis

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Innate: responds immediately to the site of injury, non-specific, no memory. Inadequate blood supply: decrease inflammatory response, compromises healing. Infection: mechanical friction, advanced age, obesity, poor general health. Injury: prostaglandins, bradykinin, chronic inflammation, lymphokines, know the neuromodulators, which are excitatory, which are inhibitory, excitatory neuromodulators, sensitize nociceptors of pns and cns by, the frequency of firing by, responsiveness, (cid:1373) the threshold, examples, histamine, substance p, glutamate. Inhibitory neuromodulators: reverse the process, (cid:1373) the rate of firing, examples, serotonin, norepinephrine, endorphins, gaba. Analgesia: mu receptor, responses include: analgesia, respiratory depression, euphoria, sedation, and decreased. Interrupt pain process to lessen the pain: enkephalins, endorphins, dynorphins, and endomorphins, present in varying concentrations in neurons of brain, spinal cord, and gi tract. And vice versa: you can"t ventilate the oxygen if you aren"t breathing it in. Inadequate ventilation causes hypoxemia: mechanism of asthma, antigen is activated, type 1 hypersensitivity immune response, mast cells, eosinophils.