MCB 2610 Study Guide - Quiz Guide: Listeria Monocytogenes, Lunch Meat, Gram Staining
8 Sep 2016
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One of the most virulent foodborne pathogens. 2500 illnesses and 500 deaths in the us/year. Disease can be mild but serious for pregnant women where it can lead to spontaneous abortion of the fetus. Petrichous flagella below 30c, no flagella at 37c. First described by egd murray in 1926 in 6 cases of sudden death of young rabbits: 1981 first diagnosed as cause of foodborne infections caused 41 cases and 18 death in halifax, Nova scotia due to eating coleslaw contaminated with sheep manure. Taken into eukaryotic host cell by phagocytosis then produces enzymes to escape phagozomes: organelle that digests food particle; listeria can escape this. Can grow in phagocytic cells and produces explosive polymerization of actin filaments to jump from cell to cell. Sensitive to alcohol-based hand sanitizers: no spores. Gram positive rods: 0. 5-2 x 0. 5 um, non-spore forming, does not form capsules. Found in raw milk, cheeses, ice cream, raw vegetables, processed meats.
