MCB 2000 Study Guide - Midterm Guide: Bond Energy, Chemical Reaction, Thermodynamics

• School: UConn
• Department: Molecular and Cell Biology
• Course: MCB 2000
• Professor: Mary Bruno

Document Summary

Kinetics: adding an enzyme will speed up the reaction, enzymes don"t alter the direction of the reaction, if there"s no energy, the enzyme can"t work in a non-favored reaction. Depends on the concentration of reactants and products. Depends on the change in bond energy between reactants and products (bonds broken) Practice problems: the first step in the metabolism of glucose involves the addition of a phosphate group catalyzed by the enzymes hexokinase or glucokinase. Glucose-6-phosphate glucose + pi dg0 = -13. 8 kj/mol atp adp + pi dg0 = -30. 5 kj/mol. The dg is positive since the concentration of products is greater than the concentration of reactants. The dg is positive since glucose-1-phosphate has more free energy than glucose-6-phosphate: when [glucose-6-phosphate] is greater than the [glucose-1-phosphate], keq > 1 and the dg is negative. The enzyme alters the equilibrium constant to favor glucose-6-phosphate. The reaction for hydrolysis has a high activation energy.