MIMG 185A Study Guide - Comprehensive Final Exam Guide - Antigen, Antibody, T Cell

• School: UCLA
• Department: Microbiology, Immunology, and Molecular Genetics
• Course: MIMG 185A
• Professor: Galic

Document Summary

Innate is found in virtually all multicellular organisms (early in evolution: characteristics/specificity often shared between organisms, pathogen recognition molecules found in the pathogen, pattern recognition molecules - molecules on bacteria that the immune system recognizes, clears most infections. Mucous membranes trap organisms spits them out or swallow them down into the stomach where they are destroyed. Interferons - protects adjacent cells from infection, limits spread of virus. Cells in the innate immune system are not antigen specific: no specific receptors for antigens, typically interact with antigens via secondary receptors (e. g. binding antibodies) Pmns = polymorphonucleocytes aka neutrophils: phagocytic - engulf particles to eliminate them, fcr: receptors on the surface of neutrophils that bind to antibodies and help engulf particles. Mast cells: have lots of granules with enzymes inside. Ige is involved in allergies: cross linking by antigen --> release of granules with histamines (almost instant)