LIFESCI 3 Study Guide - Midterm Guide: Deoxyribose, Northstar Engine Series, Histone H2B

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15 Oct 2018
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The structure of dna is critical to its function: describe in words what makes up the backbone of dna. (2 pts) Sugar phosphate backbone made up of alternating deoxyribose and phosphate connected through phosphodiester bonds between the 3" position and the 5" position: what holds the two strands of dna together? (2 pts) Rna has ribose instead of deoxyribose, uracil instead of thymine and is single stranded instead of double stranded. (could also say rna has complex secondary structures, alternative base pairing and is made in short segments compared to dna: what is it about rna that allows it to form unusual base pairs, whereas dna is restricted to the traditional base pairing? (2 pts) It can twist in all directions allowing non traditional base pairs to form: rna double helices are more stable than dna double helices and yet rna itself is less stable than dna.

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