BCH 100 Final: Learning objectives 24: Translation (Explained)

• School: UC Riverside
• Department: Biochemistry
• Course: BCH 100
• Professor: Stephanie Dingwall

Document Summary

Lecture 24: translation: terminology: triplet code, degenerate, start codon, stop codon, anticodon, wobble, aminoacyl-trna synthetase, Cca region, anticodon loop, editing site and activation site of aminoacyl-trna synthetases, n-formylmethionine (fmet), met-trnafmet, formyltransferase, shine-delgarno sequence, translocation, polysome, posttranslational modification. Set of 3 nucleotides that code for 1 amino acid. Some amino acids have more than one codon. Set of 3 nucleotides on trna that match up with the codons on mrna. base-pairing at 3rd position of codon (1st of anticodon) does(cid:374)"t ha(cid:448)e to (cid:271)e e(cid:454)a(cid:272)t. Where the amino acid gets attached recognizes the mrna site. Incorrect amino acids can be switched out for the correct ones. In prokaryotes this is the starting amino acid (fmet) Catalyzes the reaction of met + trna to from n- Purine rich region about 10 nts upstream from aug start codon. (prokaryotes) Moving polypeptide from a site to p site.