MATH 110 Midterm: Makeup Exam 1 No Solutions Fall 1996

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14 Mar 2019
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I affirm that i have neither given nor received help from any student during the period of this exam. _______________________________: a)what are the major steps for nervous system development? (5 pts, proliferation, migration & aggregation, differentiation, axon growth, synapse formation, regressive events, programmed cell death is a critical regressive process during nervous system development. At which developmental stage or time, dying neurons are found most in the nervous systems? (2 pts) What is the role of cytochrome c in the death of these neurons? (4 pts) Once released from mitochondria, cytochrome c binds to apaf1 (apoptotic protease-activating factor 1), which results in formation of the apaf1-caspase 9 apoptosome complex and activation of the caspase b). What is the role of caspase-9 and the caspase-3 in the death of these neurons? (3 pts) Caspase-9 is a specific protease that activates caspase-3. Activated caspase-3 degrades numerous protein species and causes the cell death. c).