MIC 301 Study Guide - Midterm Guide: Blastomyces Dermatitidis, Fungemia, Pneumocystis Jirovecii

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Amp b gold standard of anifungal agents. Griseofulvin, 5-luorocytosine, echinocandins do not target ergosterol. Two step treatment: high dose reduce pathogens, low dose maintenance therapy, vaccines diicult to develop because fungal metabolism similar to humans. Systemic mycoses acquired thru inhalaion and begins as pulmonary infecion and disseminates via blood to the rest of the body. What are the shared characterisics of the true pathogens: all four fungi are dimorphic ascomyecetes. Grow as mycelial thalli in the environment. Grow as spherical yeasts in the body (invasive form) Individuals working with these fungi must take extra precauions to avoid exposure. What are disinguishing features of the disease and/or the organism causing the disease: blastomyces, blastomyces dermaiidis causaive agent, endemic in se u. s. north to canada c. Relapse is common in aids paients: coccidioides, coccidioides immiis causaive agent b. In new mexico, arizona, parts of texas and northern mexico i.

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