BIOL 4376 Final: 2
29 Jul 2020
School
Department
Course
Professor
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Mmaxvid smh
Angle90 goes
deepest
so
long
needle
given
in
upper
armsggentes
WNomaxvid
catheter
Direct
injection
intoPeripheral
central
line
Time
can
vary
CBauslshort
infusion
Iconiinuous
infusion
Highest
extentarole
of
absorptionmax
wi fcan
administer
irritation
causingdrugs
thruIV vs seqim
Dosage Forms Small vs Large Special Case
Autoinjectorsm.cc
ml l7100mL g.ES sdt
administrations
igeeiniii pati ni
Examples
asup iissues
Ampou_ies rsingee.doseonyineat.s
eaeediyaa.ardose.gs
www
dose
vialsneed
to
add imay
have multivitamins
trace
elements
baderiostatic 1forparenteralnutrition
agent I
repealed
puncture
may
cause iExamples
ofWP
coring needle
tip
cuts
1am IGlass
bones
can
break
rubber
from
septum Ipre
bags uyadsorpioncsticningtopiasiicsurfacd4leachab.ksproblem
destroy
sterility I
poss pre
filled
syringe Ipros
Hard
to
break
easy add
drug
cleanest
single
dose
form lpre
infusion
bag
munichamberepn
bag
Piggyback
attached
to
existingNlineI
alsoup
Mini
bagsmall
Koone
Pvc
bag I
Injection Absorption depends on
Drugstability some
drugs
require
dose
adjustment
forim
due
to
lowerabsorptioncomparedto w
Simple aqueous based for hydrophilic drugs
Parenteral Vehicles
Simple oil based for lipophilic drugs only for 1M
Excipient aPolymers Eg Nmethyl pyrrolidine qMineral oil
bAdherents
Emulsion based for Ldrugs
Polymer based Cfor both HGLdrugs ftp.ofpdymersmethyl.gg
my drugs
leave frompolymer via dpingerm
swelling i
smallthe MW of exacepientlpelymer more
isthe
drug
dose
clearance
from
siteofinjection
1Minjections
coil
soluble cangetinto bloodafter 2processes
Elusion Dissolution
drug
particles separate drug
dissolves
fromoilparticles in blood
Adherents usedto acone ofdrug
Mmm MechanismThe
ioniccharge on the Adherent
legAinteractswith ionicdrug
Particle size
formed
