BIOL 4376 Study Guide - Final Guide: Hypermagnesemia, Tacrolimus, Hypomagnesemia
29 Jul 2020
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Document Summary
Necessary cofactor in physiologic functions utilizing atp. Primarily found in bone, muscle, and soft tissue. Kidneys excrete, reabsorbed in loop of henle and tubules. Gi losses: vomiting, diarrhea, drug- induced from ppis (omeprazole) Renal loss: loop diuretics (i. e. furosemide), cyclosporine, tacrolimus. Troponins i and t - allows cardiac muscle to contract. Cardiomyopathy: diseases that cause the heart muscle to be enlarged, thick, or rigid; causes include htn, etoh/cocaine abuse. Drug-induced cardiotoxicity (i. e. doxorubicin, fluorouracil [chemotherapy drugs]) Found in cardiac muscle; involved in cellular energy storage and transfer, sensitive marker of cardiac injury. Causes include viruses (flu, hiv, herpes), bacteria (chlamydia, gonorrhea), etoh/cocaine abuse. 12 leads created a 3d view of cardiac electrical activity. Image of depolarization/repolarization of atrial and ventricular cells that can be assessed by reviewing waves and intervals. Measure of the time between the start of q wave and the end of t wave. Prolonged qtc interval raises the risk of ventricular arrhythmias.
