BIOL 4376 Study Guide - Final Guide: Kidney Transplantation, Pulmonary Artery, Bicarbonate
29 Jul 2020
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Definition: presence of decreased kidney function (gfr < 60ml/min/1. 73m2) or kidney damage for >/= 3 months. High morbidity and mortality rates, economic burden to health-care systems from hospitalizations and high cost of chronic dialysis and kidney transplantation. Optimal organ function required normal ph (7. 35-7. 45) Cellular metabolism produces acidic substances that must be excreted to prevent acid accumulation. Lungs, kidney and a buffer system allow the body to maintain acid-base balance. Pharmacists use the abg test to assess a patient"s acid-base balance. Oxygenate the blood: inspired oxygen diffuses from alveoli into capillary blood and is bound to hemoglobin in rbcs, oxygen is carried throughout the body via arterial system, oxygen is released into tissues for utilization. Kidneys" role in maintaining acid-base balance: regulate concentrations of bicarbonate (hco3 bicarbonate, excrete acids produced by the body. Carbonic acid/bicarbonate buffer system"s role in maintaining aic-dbase balance. Carbonic acid and bicarbonate exist in equilibrium with hydrogen ions.
