ECEN 215 Study Guide - Midterm Guide: Tigrinya Language, Invitrogen, Carbamazepine

• School: Texas A&M University
• Department: Electrical & Comp Engr
• Course: ECEN 215
• Professor: Gino Augusto Chacon

Document Summary

Andreas goebel, maggie lee, f. cacciola, andy cross, paul eldridge. Perineural activity of a variety of inflammatory and immune system mediators can activate peripheral nerves leading to the perception of pain. The ability to detect such mediators in proximity to sensory nerves is therefore crucial to investigating the contributing roles of inflammation in human chronic pain. To date there is no recognized method to assess mediator profiles around human sensory nerve roots in vivo. A novel method is described that can assess these mediators in the human trigeminal system where the nerve leaves the brain stem in its pre-ganglionic portion. Mediator levels are shown to change between sample locations on the trigeminal nerve root in patients with trigeminal neuralgia. This methodology may therefore be used to shed insights as to the pathophysiology of trigeminal neuralgia, which may in turn influence clinical decisions concerning the natural history, and treatment options.