PHR 4111 Study Guide - Final Guide: Inotrope, Diltiazem, Desmopressin

• School: St. John's University
• Department: PHR - PHARMACY - PHARMD
• Course: PHR 4111
• Professor: Zito, Barletta, Ceterra

Document Summary

For afib and aflutter; prevent recurrence of pat and reduce ventricular rate in a. b. Use with gi bleed pt good for d. insipidus. Inhibition of slow inward ca current -> act on the repolarization plateau at phase 2. Indirectly cholinergic, decreasing hr and av nodal conduction. High dose for arry, low dose for hf. Decreases preload and after load by direct relaxation. Excreted mostly in bile and then renal t1/2 - 9hrs. Desmo and terlipressin (vc at high doses) are agonist (bed wetting); captains are antagonists (hyponatremia in. Flushing, dizziness, headache, cramps, nausea, pain @ inj. site. Tachyarrhythmia; pheochromacytoma; vf; exercise or high catecholamine states. Abs since they break down gut bacteria -> increased. Enhanced anesthetic; increased digoxin tox; ppt w/iv lasix like milrinone.