BIOL 303 Study Guide - Midterm Guide: Chromosomal Inversion, Heterogametic Sex, Dosage Compensation
18 Mar 2017
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Concepts & terms to know: primary sexual differentiation, secondary sexual differentiation, homogametic sex, heterogametic sex, diseases associated with x and y chromosomes, the lyon hypothesis, barr bodies, dosage compensation. Inactivation mechanism: sex determination and genotypes in fruit flies, bilateral gynandromorphy. How do barr bodies relate to dosage compensation: what does the lyon hypothesis say, explain x inactivation. Chapter 8: chromosome mutations: variation in number & arrangement. Concepts & terms to know: chromosome mutation, aneuploidy, monosomy, disomy, trisomy, euploidy, diploidy, polyploidy, nondisjunction, haploinsufficiency, autopolyploidy, autotriploids, autotetraploids, allopolyploidy, allotetraploid, endopolyploidy, deletion, terminal. Intercalary: duplication, gene redundancy, gene amplification, copy number variants. Inversion: paracentric, pericentric, translocations, reciprocal, alternate segregation, adjacent segregation. Concepts & terms to know: uniparental inheritance, endosymbiotic theory, heteroplasmy, maternal effect. Practice questions: what organelles have a part in heredity, what does the endosymbiotic theory state about these organelles and their role in heredity, true or false: mitochondrial dna (mdna) is not able to be mutated.
