01:119:115 : unit 3 objectives.pdf
30 Oct 2014
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These are meant to serve as a general guide to ensure you are covering the key points of the lectures. Feel free to contact me by email or during office hours (or lecture) to review your answers for these. You should still spend the majority of your studying time on the slides and related text. Contrast these receptors to intracellular receptors: describe the different classes of molecules that can function as second messengers and the enzymes/factors involved in their production/release. Understand the advantage of using second messengers over proteins in a signal transduction pathway: understand the importance of turning off cell signaling pathways, including gpcr and rtk pathways, and what is involved. Understand how a mutation in ras leads to a constitutively active signaling pathway: explain the role of no in paracrine signaling. Any pathways not discussed in lecture that are in the text, you are not responsible for.
