BIOL 44400 Study Guide - Midterm Guide: Missense Mutation, Nonsense Mutation, Twin Study

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scarletcrab513

19 Dec 2015

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Biol444 exam 1 fall 2015 100 points. Multiple choice: choose the best answer and bubble it in on the scan sheet (n=25, 2 pts each) Modifications to dna, such as methylation, that don"t alter the sequence yet can be passed from one generation to the next are termed ________ a. ) epigenetic b. ) permanent c. ) endocrin d. ) polygenic e. ) histrionic. In a study of the genetics of a trait, 384 pairs of twins were enrolled. In 82 pairs, neither twin expressed the trait. In 206 of the remaining pairs, both twins expressed the trait. What is the concordance in this study? a. ) Two daughter cells are produced per cycle b. ) Daughter cells are genetically identical c. ) the chromosome number of daughter cells is half that of the parent cell d. ) both b. ) and c. ) are correct e. ) both a. ) and c. ) are correct. Which of the following is a transition? a. ) Which of the following is a characteristic of rna? a. )

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QUESTION 1

Jim is blood type A, his brother John is type O and his sister Jane is type AB. What are the genotypes of their parents?

Which of the following is true for alleles that show incomplete dominance?

Heterozygotes have a genotype like the dominant allele.

Homozygotes have a genotype like the recessive allele.

Heterozygotes have a phenotype intermediate between the dominant and recessive alleles.

Homozygotes have the same phenotype as the heterozygotes.

QUESTION 3

Which principle of inheritance concluded that when games are formed in meiosis, the two alleles of each gene separate from one another, and each gamete receives only one allele?

independent assortment

Which term best describes a condition in which alleles at one locus can alter the expression of alleles at another locus?

polygenic inheritance

A single unit of genetic information located on a chromosome defines:

The physical expression (appearance or function) of an organism's genes defines:

genotype

a single characteristic

Palomino horses (golden color with a blond mane) are an incompletely dominant trait produced by the combination of the chestnut color allele and the cream color allele. If you wanted to produce as many palominos as possible, which mating strategy below would be the best choice?

Which term best describes the effect of a single gene on multiple aspects of the phenotype?

polygenic inheritance

QUESTION 9

Which term best describes the separate expression of both alleles for a single trait in the same cell?

polygenic inheritance

QUESTION 10

One form of a gene found on a single chromosome defines:

A chocolate lab (whose mother was a yellow lab) is mated with a black lab whose genotype is BbEe. What fraction of the offspring would be expected to be yellow labs?

What type of allele is always expressed regardless of whether the individual is homozygous or heterozygous for it?

Both the dominant and recessive alleles

Given the parents AABBGgHhrr Ã AabbGgHhRr, assume simple dominance and independent assortment. What proportion of the progeny will be expected to have the genotype AaBbggHHrr?

___________________ is defined as having two of the same type of allele for a particular trait.

The physical position of an allele on a single chromosome defines:

Which term best describes two or more genes affecting the phenotype in an additive fashion?

codominance

polygenic inheritance

Multiple choice.

1.Origins of replication...

A. occur at many sites on bacterial and human chromosomes

B. contain one replication fork each where the daughter stands are being sythesized

C. initiate replication in a uni-directional manner

D. result in bubbles opened by helicases

E. occur at one site per chromosome

2.Telomerase...

A. is important for the replication of circular chromosomes

B. is important for the replication of linear chromosomes

C. carries a template in the form of a DNA molecule

D. sythesizes RNA primers

E. both the 1st and 2nd option are correct

3.What are topoisomerases?

A.Enzymes that lay down an RNA primer during DNA synthesis.

B.The ends of the chromosomes.

C. Proteins that unwind DNA.

D. A strain of mice.

4.Which enzyme produces the first piece of nucleic acid synthesized in DNA replication?

A. Primase

B. DNA polymerase

C.ORC

D. DNA ligase

5. Which of the following does not contribute to the mutagenesis of our DNA?

		A. alterations to bases (nucleotides) that change their hydrogen bonding characteristics
		B. passing on of mismatched DNA into daughter cells
		C. inefficiency of MutS to recognize errors in base pairing
		D. DNA polymerase slipping during synthesis and creating insertions or deletions
		E. DNA polymerase erroneously synthesizing DNA in the reverse direction during S phase

1) The hypohyseal portal veinsdrain the

A) Anterior pituitary.............is this the correctanswer?
B) Posterior pituitary
C) Hypothalamus
D) Thalamus

2) The interstitial cells of thetestes are an important target for

A) FSH
B) LH.............is this the correct answer?
C) GnRH
D) Oxytocin
E) Both A and B

3) During spermatogenesis, which ofthe following undergoes a meiotic division to produce haploidcells?

A) Spermatids
B) Secondary spermatocytes
C) Pimary spermatocytes.............is this the correctanswer?
D) Spermatogonia
E) Spermatozoa

4) The normal number of spermatozoaper milliliter of semen is:

A) 50-100

B) Fewer than 20,000,000

C) More than 200,000,000

D) 50,000,000 â 150,000,000.............is this the correctanswer?

E) About 5 million

5) A normal mature humanspermatozoa contains:

A) 23 chromosomes.............is this the correct answer?

B) 23 pairs of chromosomes

C) 46 chromosomes

D) 46 pairs of chromosomes

6) During the menstrual cycle, LHis at its highest levels

A) During the menstrual phase

B) Just prior to ovulation.............is this the correctanswer?

C) Just after ovulation

D) Just before menstruation begins

E) Levels of LH never change

Thank you in advance!

harlequinporpoise202

BIOL 44400 Study Guide - Midterm Guide: Missense Mutation, Nonsense Mutation, Twin Study

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