PSYC 4510 Study Guide - Midterm Guide: Nigrostriatal Pathway, Monoamine Transporter, Catechol

• School: Northeastern University
• Department: Psychology
• Course: PSYC 4510
• Professor: Richard H.Melloni Jr

Document Summary

Ionotropic receptors: transmitter binding opens channel: metabotropic receptors: transmitter binding releases 2nd messenger inside cell, time delay compared to ionotropic. Inactivation: reuptake: transporters return extra neurotransmitter to terminal for repackaging or metabolism. Chapter 6: serotonin: culprit for almost all evil and source of all good, synthesis, tryptophan hydroxylase is rate limiting step, conversion of 5htp to 5ht by aada by removal of carboxyl group (same process as for. Inactivation: reuptake, choline transporter (only choline is reused, acetic acid is metabolized, metabolism, acetylcholinesterase (ache) changes ach to choline and acetic acid, drugs that block ache increase ach activity. Irreversible drugs can cause death: reversible drugs can be metabolized, ach system, neurons clustered within select brain regions. Interneurons (striatum: projecting neurons (septum, pons, non-projecting (caudate-putamen and nucleus accumbens, receptors, 2 subtypes, nicotinic, found on muscles, ganglia (pns) and certain cns regions, 5 subunits: both alpha subunits must be occupied to open channel.