PSYC 4510 Study Guide - Midterm Guide: Drug Delivery, Bioequivalence, Helicopter Flight Controls
2 Apr 2018
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Neuropsychopharmacology: drug-induced changes in the function of select neurons that influence specific behaviors. Therapeutic vs side effects: therapeutic: desired physiologic and/or behavioral effect, side: all other drug effects varying from annoying to dangerous. Specific vs non-specific effects: specific: due to physical/biochemical interaction of the drug with a target, non-specific: not based on drug/target interaction (eg. placebo) Intravenous administration (iv: rapid and accurate, reaches the brain almost instantly, hazardous, requires careful monitoring and sterilization. Slow and even delivery: best for lipophilic drugs (membranes are fatty, often painful, more so if there"s oils. Identical doses can have different concentrations over time depending on method of administration. Salt forms: increases aqueous solubility, facilitating solution in stomach: but: adds to the weight of the drug without increasing the amount of drug. [unbound] diffuses across membrane and [unbound] in blood is replaced by drug from. One drink an hour: zero order transformation: when [drug to transform] > [converting enzymes], body can"t keep up (ex.
