BIOL 1119 Study Guide - Final Guide: Renal Function, Macula Densa, Peritubular Capillaries
3 Oct 2017
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Document Summary
Control of gfr: gfr is the amount of filtrate formed per minute by both kidneys. In general, constrict afferent arteriole (aa) and/or dilate efferent arteriole (ea): lower pressure in glom: decrease the gfr. In general, dilate aa &/or constrict the ea: increase pressure in glom: increase the gfr. Renal autoregulation of gfr: renal autoregulation the ability of nephrons to adjust their own blood flow and gfr locally without external control. Use autoregulation to maintain a relatively stable gfr even if bp changes. Myogenic mechanism: the tendency of smooth muscle to contract when stretched tubuloglomerular (tg) feedback: several structures at end of nephron loop: myogenic mechanism. Myogenic mechanism responds to immediate pressure changes at entrance to glomerulus to maintain the same pressure inside glomerulus. In order to keep gfr constant in face of systemic bp fluctuations. Myogenic mechanism: bp less stretch of the aa; aa dilates in response, decreases resistance in response to decreased blood pressure at entrance of glomerulus.
