Choose only one correct answer
QUESTION 1
Transautophosphorylation occurs in which two of the followingsignaling pathways?
a.GPCR and RTK pathways
b.RTK and Integrin/FAK pathways
c.S/TKR and PKA pathways
d.GPCR and Ras pathways
e.MAPK and cAMP pathways
QUESTION 2
Which of the following receptors are activated by GTP?
a.G protein coupled receptors only
b.tyrosine kinase receptors only
c.both G protein coupled receptors and tyrosine kinasereceptors
d.neither G protein coupled receptors nor tyrosine kinasereceptors
QUESTION 3
Why can both GPCR and RTK pathways activate calmodulin?
a.Because both activate PLC
b.Because both activate PI3K
c.Because both trigger an action potential
d.Because both activate Ras
e.Because both activate PKA
QUESTION 4
Ion channel receptors __________ enzymes. They __________ bindsignaling ligands.
a.are, do
b.are not, do
c.are, do not
d.are not, do not
QUESTION 5
PIP2 is cleaved by ___________ to produce _____________.
a.phosphodiesterase, DAG and IP3
b. phospholipase C, DAG and IP3
c. phosphodiesterase, DAG and calcium
d. phospholipase C, DAG and calcium
QUESTION 6
Why are integrins considered to be signaling proteins?
a.Because they bind ECM
b.Because they bind heterotrimeric G proteins
c.Because they bind FAK
d.Because they bind MAPK
e.Because they bind Sos
QUESTION 7
Why isn’t tubulin considered a G protein?
a.Because it doesn’t propagate a signal in a signalingpathway
b.Because it doesn’t bind to GPCR
c.Because it doesn’t bind to a GEF or a GAP
d.Because it doesn’t undergo transautophosphorylation
e.Because it doesn’t bind GTP