ZOL 141 Study Guide - Klinefelter Syndrome, Cytogenetics, Isotretinoin
Document Summary
Cell organelles: nucleus, nucleolus, e. r, ribosomes, golgi f, mitochondria. X linked recessive: phenotype expression is more common in males, affected males receive allele from mother and transmit to all daughters but no sons, examples: color blindness, muscular dystrophy, hemophilia a & b, maternal mitochondia, passed from mother to child through cytoplasm of egg, all of your mitochondria come from your mother. Risk of reoccurrence for multifactorial disorders: consanguinity, previously affected child, severity of defect, higher frequency in one sex, heritability h an expression of how much of the observed variation in a phenotype is due to differences in genotype, h can be from 0 1, 0 being no genetic variance, 1 being all genetic variance ii. (genotype variance) / (phenotype variance) Karyotype complete set of chromosomes of a cell that has been photographed during cell division and arranged: can be made from, white blood cells, skin cells, amniotic fluid cells, chronic villus cells.
