KINE 408 Study Guide - Final Guide: Carnitine O-Palmitoyltransferase, Carnitine, Peanut Butter
Document Summary
L carnitine: amino acid produced by the body, taken to increase l-carnitine levels in the body in people whose levels are too low. Comes from endogenous synthesis occurring the liver and kidney. Distribitued to tissues and organs whose metabolism is dependent on fatty acid metabolism. Muscles concentrate up to 95% of all l-carnitine present in the body. Most important function to transport fatty acids into the mitochondria. Reduced carnitine level in vegetarians l-carnitine reduces lactate accumulation in skeletal muscle by reducing use of glycogen for production of atp. Most available: other amino acids converted from l-carnitine. Propionyl- l- carnitine- for heart and vascular disease. Antioxidant and anti-inflammatory activity on endothelial cells (5) Substrate for carnitine palmitoyl transferase in fatty acid translocation in the mitochondria for b-oxidation formation of acetylcarnitine during high intensity exercise for the maintence of co-enzyme a. L carnitine combined with carbohydrate ingestion may possibly increase muscle carnitine content.
