PCB 4674 Study Guide - Midterm Guide: Quantitative Trait Locus, Ronald Fisher, Twin
8 Nov 2016
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Chapter 9- evolution at multiple loci- quantitative genetics. Quantitative genetics: the branch of evolutionary biology that provides tools for analyzing the evolution of multilocus traits; usually continuous: qualitative traits: distinct, easy to see phenotypes (red flowers or yellow, you have ms or nah) Edward east (1916)- longflower tobacco- length of the corolla; determined that qualitative traits are determined by the combined influence of mendelian alleles at many loci. Small differences are due to environmental changes: ***quantitative traits are determined by the combined influence of the. Genotype at many different loci and the environment**: quantitative trait loci (qtls): portions of the genome that influence quantitative traits. Ronald fisher: alleles driven to fixation by natural selection virtually all play a small role in phenotype. H. allen orr: some alleles fixed during adaptive evolution exhibit large phenotypic effects: heritability: the fraction of the total variation in a trait that is due to variation in genes, narrow-sense heritability: h2.
