NEUROSCI 223 Study Guide - Midterm Guide: Resting Potential, Lipid Bilayer, Voltage Clamp
7 Apr 2016
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How does this differ from a passive, graded electrical response: all action potentials are exactly the same. Why: how is information encoded by action potentials, understand the following terms/notation: depolarize, repolarize, hyperpolarize, subthreshold, superthreshold, eion, iion,vm, vrest, (and gion, which is conductance ) At rest, cytoplasm is 30-100mv more negative than outside inside outside = negative resting membrane potential. Vm,rest = inside minus outside = minus resting. Eion is the nernst potential for an ion. Nernst potential = reversal potential = equilibrium potential: membrane potential at which the force of diffusion of an ion due to concentration gradient is exactly opposed by the force of diffusion due to a separation of charges. Because of active transporters that maintain gradients (na/k pump) Bulk solutions inside and outside of the cell are electrically neutral! About 30x more k+ inside than outside the cell. About 30x more na+ outside of the cell than inside.
