NURS 321 Study Guide - Final Guide: Cystine, Nystagmus, Nursing Assessment
17 May 2021
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Local tissue inflammation and localized symptoms plus extra-articular manifestations. Autoimmune autoantibody presence in response to abnormal antigens (unclear) Form immune complexes within synovial membrane or cartilage. Insidious fatigue, anorexia, weight loss, generalized stiffness, low grade fevers. These symptoms often occur before joint pain or inflammation becomes specific to a joint. Joint pain and stiffness after inactivity (worst in the morning) Warmth, inflammation, and sometimes redness at joints. Small joints of hands and feet (affects fingers and toes) Boutonniere deformity of thumb resembles hitch hiker"s thumb. Ulnar deviation of metacarpophalangeal joints outward drift. Swan neck deformity of fingers zig zag. Rheumatoid nodules- in 20-25% of ra patients. Eye inflammation, cataracts or loss of vision. Sjogren"s syndrome- found in 10-15% of ra patients. Felty syndrome (rare) splenomegaly and leukopenia. Medication/drug therapy- nsaids/aspirin, dmards, biological response modifiers or target therapies, corticosteroids, immunosuppressants. Pt and ot adls and rom exercises. Focus on joint protection promote strength and mobility and safety.
