ESPM 108B Final: Final Review

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Document Summary

Time: longer duration - more likely to have greater genetic diversity (bc mutations take time) Assume constant rate, not driven by anything (just an assumption, not always true) Differs depending on marker (mt/nuc/chl), microsat rate higher than snps. Migration: the most potent force in limiting pop divergence. Drift: creates divergence, more important in small pops, initially, doesn"t change gd in overall pop if occurring in subpops. First based on neutral processes - balance btw drift and. Branch lengths relatively short in present time, longer as you go back bc of geometric process that produces the current allelic variability. Compressed to recent times if had just gone through bottleneck - same as if selection had been happening. Bottleneck: genome wide - indep of site. Selection: only for the region under selection, rest of genome showing neutral pattern. Allele freq in and among pops: the only way evolution occurs. Allele frequencies and what they add up to.