BIOL 1020 Study Guide - Midterm Guide: Okazaki Fragments, Calico Cat, Epistasis
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BIOL 1020 Full Course Notes
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Document Summary
Codons (three base sequences that are on the mrna), initiation complex 30s ribosomal subunit, 50s ribosomal subunit, mrna and trna along with initiation factors; methionine = start codon (eventually cleaved off of the polypeptide chain) Binds to the p site at beginning, second amino acid than binds to the a site, new. Amino acids enter at the a site, new amino acids are added at the p site. Ribosome dissociates and the rna and proteins are released. Message can be read sequentially by more than one ribosome. Eventually the message in mrna is broken down. Sometimes proteins can undergo post-translational modifications (ex: stomach enzymes; pepsin) Sickle cell anemia: most common inherited disease in the south. Inherited as an autosomal recessive disorder, malformed hemoglobin, heterozygote superiority. Down syndrome (trisomy 21) aneuploidy; most common aneuploids. Tay sachs: recessive lethal (100% penetrance), some evidence that the heterozygous condition makes a person less likely to die from tb.
