BIOL 1000 Study Guide - Final Guide: Deoxyribonuclease, Heterochromatin, Noncoding Dna

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# of purines equals # of pyrimidines. Polynucleotide: deoxyribose sugars are linked by phosphate groups in an alternating sugar-phosphate-sugar patter forming a sugar-phosphate backbone: has polarity. Phosphodieste(cid:396) (cid:271)o(cid:374)d: ea(cid:272)h phosphate g(cid:396)oup is a (cid:862)(cid:271)(cid:396)idge(cid:863) (cid:271)et(cid:449)ee(cid:374) the 3" (cid:272)a(cid:396)(cid:271)o(cid:374) of o(cid:374)e sugar and the 5" (cid:272)a(cid:396)(cid:271)o(cid:374) of the (cid:374)e(cid:454)t suga(cid:396); the e(cid:374)ti(cid:396)e li(cid:374)kage. Double helix model: watson and crick, 2 sugar-phosphate backbones are separated from each other. The two strands of a double helix fit together in a stable chemical way only if they are. Antiparallel (cid:894)o(cid:374)l(cid:455) if the(cid:455) (cid:396)u(cid:374) i(cid:374) opposite di(cid:396)e(cid:272)tio(cid:374)s . the 3" e(cid:374)d of o(cid:374)e st(cid:396)a(cid:374)d is opposite the 5" e(cid:374)d of its (cid:272)o(cid:373)ple(cid:373)e(cid:374)ta(cid:396)(cid:455) st(cid:396)a(cid:374)d(cid:895) Semiconservative replication: watson and crick, hydrogen bonds between the two strands break, allowing them to unwind and separate. Each strand, then, acts as a template for the synthesis of its partern. Dna polymerase: enzymes that assemble individual deoxyribonucelotides to form complementary polynucleotide during replication.

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