PS280 Study Guide - Final Guide: Sensitivity And Specificity, False Positives And False Negatives, Penetrance
Document Summary
The degree to which a dominant gene manifests in the general population. Incomplete penetrance: proportion of people w dominant gene will fail to show its effect. Penetrance of schizophrenia gene may be less than 100%, closer to 50% Sensitivity: correctly identifies those w the disease (true positive rate) Specificty: ability of test to correctly identify those w/o the disease (true negative rate) True negative: does not detect condition when the condition is absent. False negative: does not detect condition when condition is present. Schizophrenia marked by heterogeneity; people from v different backgrounds experience it. Makes it difficult to predict how person will be affected and future prospects. Knowing that other people are experiencing the same thing you are going through. Can help with the healing process (group therapy) From low ses, being black, child of parent w schizophrenia has 10x normal risk, early trauma, using marijuana, bullying. Absence of typical behaviours/experiences + deteriorated academic/occupational proficiency.
