Physiology 2130 Study Guide - Midterm Guide: T-Tubule, Sliding Filament Theory, Troponin C

• School: Western University
• Department: Physiology
• Course: Physiology 2130
• Professor: Carlie Bell

Document Summary

A muscle is composed of bundles of fasciculi, which are made up of many muscle cells (also called muscle fibres). Each of these cells contains bundles of myofibrils. Thin myofilaments mostly contain the protein actin and troponin and tropomyosin. This interaction between thick and thin myofilaments results in muscle contraction. Each fascicle is surrounded by connective tissue called perimysium. The two types of myofilaments that compose the myofibril are the contractile elements of muscle. This network contains calcium ions, which are essential for contraction: near the end of sr is the terminal cisternae, which is close to the t- This picture shows nicely how transverse tubules go deep into cell to conduct action potential. Also shows how close terminal cisternae is to transverse tubule. Thin myofilament: recall thin myofilaments are composed of the globular protein actin. *** at rest, troponin complex holds tropomyosin over myosin binding site on actin.