Pathology 2420A Study Guide - Midterm Guide: Phagocytosis, Immunoglobulin G, Chemotaxis
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Binds directly to microbe that needs to be getting rid off. Cells that are opsonized can result recruit other cells. C3b helps opsonize cells helps them be lysed. Mac end product physically lyses the cell by punches wholes in the cell. One cell on its own will never divide. Needs other cells to signal it to divide. Contact inhibition= if you let them give dividing, they will only stop when there is no more room or too crowded, no nutrients, etc. To recruit you need to have labile cells (only cells that differentiate) Certain factors come in and recruit g0 to g1 cells. Important because most cells in body are adherent. If adherent it needs to be stuck to something to divide. Matrix provides something for the cell to sit on. Cell binds to ecm (fibrin, collagen, etc. ) so it can sit and grow. Lymphocytes we can assume are t cells and b cells.