[Pathology 3240A] - Midterm Exam Guide - Everything you need to know! (24 pages long)

• School: Western University
• Department: Pathology
• Course: Pathology 3240A
• Professor: Geordie Shepherd

Document Summary

Rudolph virchow: father of cellular pathology: described the cellular basis of disease by saying that every disease happens at the cellular level. Cells constantly use energy to stay in homeostasis with their environment. A cell can only exist in a narrow physiological change. Cell membrane begins to break down in cell injury. If environmental changes exceed the capacity of the cell to maintain homeostasis, you get cell injury. Normal cell environmental changes increased stress adapt for new homeostatic state or undergo cell injury/cell death (adapt or die) Reaction of a cell to stress can range from mild/completely reversible, to a long-term adaptive change, or to irreversible damage & cell death. The left ventricle must be the strongest part to pump blood into the arteries. But if the valve that the blood flows through is getting hard, it puts extra pressure on the left ventricle. Then myocytes get bigger (hypertrophy) to overcome resistance.