Microbiology and Immunology 2500A/B Study Guide - Final Guide: Cryptococcus Neoformans, Malassezia, Hymenolepis Nana
10 Sep 2020
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Eukaryotes more related to us than bacteria. Plant-like forms but lack defined root or leaf structures and are non-photosynthetic. They are assigned to their own kingdom, mycota. Saprophytic (growing on dead, organic matter) or parasitic. Unusual metabolic products can be toxic to higher animals. Clinical classification: yeasts sessile growing (grow flat and divide similar to bacteria, molds have hypha tubes that exporiolate, dimorphic fungi, poisonous mushrooms (homobasidiomycetes) mycetism. **mushrooms are associated w/lower risk of cardiovascular disease. Grow in a manner similar to bacteria but 10x larger. Not much of a hazard to laboratory workers. Used for commercial production of alcohol and citric acid. Normal flora of the oropharynx, vagina, bowel and skin. Causes acute and chronic superficial infections of the skin (diaper rash, balanitis, intertriginous areas [ skin on skin]), nails (paronychia), mucous membranes (thrush, vaginitis), uti. In immunocompromised patients, severe systemic infections (esophagitis, pyelonephritis, sepsis: albicans satellite lesions. Continuous red patch outliers on their own.
