Microbiology and Immunology 2500A/B : Kang_Notes
10 Dec 2013
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Rna polymerase in virus particles b/c as they get into cells they can translate genomic. Some of these mutations can give different types of diseases. Dna from nucleus to cytoplasm which is then translated to make a protein: dna exists as dsdna & is trying to transcribe to make mrna, mrna is transported. & if it is ssrna that has 3 diff polarities if theres -ssrna, how it replicates & how it transcribes, if its + ssrna, how does it rep & thing if its retrovirus, goes through dna intermediate . Major viral diseases: smallpox* require the vaccination for small pox. Site of action of protease inhibitors: viral assembly and release, once all proteins & genome is made, need virus to assemble itself. Viral diseases to learn: human immunodeficiency virus (hiv) and acquired immunodeficiency syndrome (aids, viral hepatitis a,b,c, ebola hemorrhagic fever and hantavirus pulmonary syndrome (hps, influenza and severe acute respiratory syndrome (sars, viruses and cancer.
