Biology 3316A/B Study Guide - Midterm Guide: Phosphatidylinositol 4,5-Bisphosphate, Phosphatidylinositol 4-Phosphate, Calcium Imaging
Document Summary
Membrane) composition affects membrane curve,pc = flat,pe = curve. C)dag and ip3 2nd mess. formed from pi pi + pi4k -> pi4-phosphate(pip) + pip5k -> pi4,5-biphosphate(pip2) + phospholipasec --> dag+ip3. Actionpotential) na/k pump causes gradient -> resting membrane potential (rmp, inside -60mv, outside +50mv) sodium out, potassium in. Resting state k channel partly open na closed (pos cytosol)/ depol k partly open, na open (pos cytosol)/ repol k open, na closed (neg cytosol) Repol causes restoration of rmp, 4ms between depol and repol, hyperpol (-55mv) due to k channel open during repol. Action potential moves one direction only b/c na channels close during repol and na channels further ahead yet to be depolarized. Chemical signal transmit info between neurons, electric sig must be converted to chemical sig for info to be passed along to next dendrite.