Biology 1002B Study Guide - Midterm Guide: Phos, Facilitated Diffusion, Macromolecular Crowding

• School: Western University
• Department: Biology
• Course: Biology 1002B
• Professor: Tom Haffie Denis Maxwell

Document Summary

Points of control for regulation of protein abundance: transcription control, translation control, proteins are coded for by genes in the dna, requires transcription (dna rna) in nucleus, requires translation (mrna protein) in cytosol. Increase in protein means increase in transcript: transcript abundance is based on two competing processes, rate of transcription, rate of mrna decay. Incorrect to say that increase in transcript=increase in rate of transcription because it could be the decrease in mrna decay. If mrna transcript life is long, get more proteins translated from it. If mrna transcript is short, less protein is translated from it: less mrna usually means less proteins as well. The different classes of amino acids: non polar amino acids, uncharged polar amino acids, negatively charged (acidic) polar amino acids, positively charged (basic) polar amino acids. Primary structure sequence: unique sequence of amino acids forming a polypeptide, determined by the nucleotide. What drives protein folding, and what defines denaturation.