Biology 2581B Study Guide - Final Guide: Meiosis, Tryptophan, Methionine

• School: Western University
• Department: Biology
• Course: Biology 2581B
• Professor: David R Smith

Document Summary

Polycistronic transcript: multiple genes on one mrna. Nal coxi protein has 15 more aa than human coxi protein. Pre-mrna = 29 902nt mrna = 1587nt. Live in the small intestine of host. Ribosomal slippage: recognizes frame-shift mutation"s motifs / hotspot for mutation & skips the codon (aggy = 1; ccccu = 2) Different motifs = different number of codons skipped. Deleterious mutations in other organisms (ex: non-sense mutations) could be overcome. Contains non-coding dna between exons (not introns, large in size) Not spliced out = functional non-coding = form an internal loop. Translational bypassing: ribosome skips & jumps when it hits the internal loops, parts of the sequences are not translated. The nal mrna transcript will contain extra non-coding sequences. Gene b is in gene a"s introns; a self-splice = mrna transcript of b. Gene a and gene b are translated individually. More than 1000 in total of the genome.