Biology 2581B Study Guide - Quiz Guide: Progressor, Somatic Cell, Chromosome
15 May 2020
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Document Summary
Developmental biology: fate maps are created to trace cell lineages, direct observation of embryos, dye marking. But every cell division leads to the dilution of dye. Fluorescent dyes have a higher intensity but they are not permanent: genetic labelling. Permanent labelling of cells and their progressors. Differential gene transcription regulates which genes are transcribed into nuclear. Eukaryotic dna forms complex with proteins (= histones: h1, h2a, h2b, h3, h4) Activator of transcription: histone acetyltransferase places acetyl groups on histones, histone deacetylases removes acetyl groups from histones, histone methyltransferases places methyl group on histones, histone demethylase removes methyl groups from histones. Promoter: site where rna polymerase binds, contains tata sequence. Needs additional proteins to bind: tata-binding protein (= tbp); Tfiia - tfiih: needs additional flanking sites cpg islands. Enhancer: controls efficiency and rate of transcription, bind specific proteins = transcription factors.
