Biology 2581B Study Guide - Final Guide: Zygote, Woolly Mammoth, Inverted Repeat
21 Apr 2017
School
Department
Course
Professor
Document Summary
If we compare a mouse vs. human genome, at the sequence level there are many similarities. Same types of genes, genes with similar sequences. We can use dyes to label chromosomes, creating a staining pattern. Comparison of staining patterns between mouse and human genomes were quite different: 20 mouse vs. 23 human chromosomes. Through genome sequencing, we found similar pieces between both genomes, but we would have to manipulate the sequences to achieve this similarity. Each colour here represents a different chromosome. Over evolutionary time, rearrangements occurred which account for these differences. Most chromosomes need rearrangements in order to account for gene content. Think of chromosomes as packages of a certain size, with a certain content. In the map shown here, we lined all the chromosomes from one species as a circle. The next circle has chromosomes where we tried to align them with the rice chromosomes: very few gaps, but in general, this is very possible.
