PSL300H1 Study Guide - Final Guide: Visual Acuity, Metabotropic Glutamate Receptor 6, Retina Horizontal Cell
Document Summary
On (light-on): bipolar cells have a metabotropic glutamate receptor, mglur6, hyperpolarizes cell when binds glutamate. cells are active in light, when less glutamate secreted by photoreceptors. Off (light-off): bipolar cells have ionotropic glutamate receptors that depolarize cells when binds to glutamate. these cells are active in darkness. 80% of retinal ganglion cells = p or m cells. Glaucoma leading cause of blindness, degeneration of optic nerve. associated with increased inraocular pressure, sometimes caused by excess aqueous humor (ex. canal of.
