PSYC62H3 Study Guide - Midterm Guide: Skeletal Muscle, Metabolite, Neurotransmitter
Document Summary
Absorption time: quicker than oral or more stable: inhalation. Absorbed through skin, commonly through a skin patch. Absorption time: quicker than oral: nasal and mucosal membrane. Absorbed through membranes in nasal passages or mouth. Drug broken down into metabolites by enzymes. Metabolite: product resulting of enzymatic transformation of a drug. First-pass metabolism: metabolism that begins to occur before the drug reaches the site of action. Pro-drug: biologically active compound converted through metabolism, from an inert substance, elimination. Drugs or metabolites or both are eliminated from the body. Elimination rate: amount of drug eliminated from the body over time. Half-life: duration of time necessary for the body to eliminate half of a drug. Metabolic receptors: agonist (on, antagonist (fail to turn on, partial agonist (weakly turn on, inverse agonist (off) Does not block, but still prevents the binding of neurotransmitters: partial agonist, antagonist, neurotoxins.
