[BIOD35H3] - Midterm Exam Guide - Comprehensive Notes for the exam (21 pages long!)

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With few exceptions, the cardiovascular response to exercise is directly proportional to the skeletal muscle oxygen demands for any given rate of work, and oxygen uptake (vo2) increases linearly with increasing rates of work. At rest, the skin and skeletal muscles receive about 20 percent of the cardiac output: during exercise, more blood is sent to the active skeletal muscles, as body temperature increases, more blood is sent to the skin. This process is accomplished both by the increase in cardiac output and by the redistribution of blood flow away from areas of low demand. Without such a resetting, the body would experience severe arterial hypotension during intense activity: mean arterial pressure is generally much higher in hypertensive patients, likely owing to a lesser reduction in total peripheral resistance. Evidence suggests that the capillary density of the ventricular myocardium can be increased by endurance exercise training.