BIOA01H3 Study Guide - Final Guide: Thermus Aquaticus, Okazaki Fragments, Heterogametic Sex

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15 Dec 2013
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BIOA01H3 Full Course Notes
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BIOA01H3 Full Course Notes
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Lec 13: dna the stuff of heredity to investigate a crime scene, collect blood sample and look at dna. It"s hereditary: comes from parents, can"t hide it. How do we know dna is hereditary material? (p. 188) Hershey & chase analyzed the cell surface coat-containing part for radioactivity: results: Progeny phage that had radioactive sulphur did not contain radioactivity. Phage that had radioactive phosphorus containing dna did contain radioactivity: conclusion: dna is hereditary material b/c the hereditary material that was transmitted was labeled with p which labels dna. Nucleotides composed of: phosphate group, sugar, base: purines (adenine & guamine) and pyrimidines (thymine & cytosine) Watson & crick discovered structure w/ help from wilkins and franklin. *bold = noble peace prize: franklin did xray defraction of dna molecule and found that when looked upon from above, appeared egg-shaped/helical, dna = spiral staircase. Semi conservative: each strand produces its own template and that served as template for next model.