MIC 4124 Study Guide - Midterm Guide: Gram-Positive Bacteria, Superantigen, T Helper 17 Cell

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Document Summary

Lecture 5: host response to bacterial pathogens part 2. Lymphocytes are activated in certain mucosal sites and can home in to other mucosal sites. Our focus is on the gi tract / intestine. Part of the immune system of the gi tract. These are organized lymphoid nodules usually found in the lowest portion of the small intestine (ileum) Both the mesenteric lymph nodes and peyer"s patches are involved with the small intestine. The gi tract is similar to the respiratory tract. However, the gi tract has columnar epithelial cells. Lots of vili in the small intestine = increased surface area. Within vili, there are enterocytes (epithelial cells in the gut) Below the crypt enterocytes are stem cells for generating enterocytes. Found in the si and not the li. Many lymphocytes are embedded in the gut epithelium. M cells are present in the epithelium over top the peyer"s patch. Proximal = 105 to 107 bacteria / ml.